Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075376 | 0.83 | LMNA (0.53) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL24922128 | 0.83 | KMT2A (0.52) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL12896223 | 0.83 | KMT2A (0.51) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL30212531 | 0.81 | NPC1 (0.57) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL46317 | 0.77 | KDM4E (0.58) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL24921496 | 0.77 | NPC1 (0.42) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL31516755 | 0.77 | KDM4E (0.58) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL12989738 | 0.77 | LMNA (0.50) | KMT2AMEN1CYP1A2CYP2C19LMNA | |
| SCHEMBL24920394 | 0.77 | NPC1 (0.49) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL12706294 | 0.76 | LMNA (0.49) | KMT2AMEN1CYP1A2CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910171-A | Method for preparation of 6-11 bicyclo erythromycin derivant | ENNATA PHARMACEUTICALS INC (US) | 2007-02-07 | — | — | CN | claimed |
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |
| US-9149465-B2 | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-8927551-B2 | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8765735-B2 | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |