Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15849062 | 0.83 | KMT2A (0.61) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL24922678 | 0.82 | NPBWR1 (0.37) | KMT2AMEN1HPGDNPSR1LMNA | |
| SCHEMBL27233918 | 0.82 | CHRNA7 (0.39) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL27233916 | 0.82 | CHRNA7 (0.39) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL24922287 | 0.81 | GRN (0.37) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL30212531 | 0.80 | NPC1 (0.57) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL27233975 | 0.77 | KMT2A (0.40) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL27233970 | 0.77 | KMT2A (0.40) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL24922131 | 0.75 | KMT2A (0.39) | KMT2AMEN1CYP1A2CYP2C19KDM4E | |
| SCHEMBL30988311 | 0.75 | KMT2A (0.39) | KMT2AMEN1CYP1A2CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |