Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18652132 | 0.85 | NR4A1 (0.52) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL31060098 | 0.82 | NR4A1 (0.53) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL3792155 | 0.82 | NR4A1 (0.53) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL18650130 | 0.81 | NR4A1 (0.47) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL10407111 | 0.80 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL3624003 | 0.76 | OPRM1 (0.56) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL27794823 | 0.75 | CDC25B (0.50) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL21243055 | 0.75 | CDC25B (0.54) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL10995822 | 0.75 | NR4A1 (0.57) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL28616637 | 0.75 | NR1I2 (0.54) | NR4A1NR4A2NR4A3PTPN1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765667-B2 | HCV protease inhibitors | EISSENSTAT MICHAEL (US) | 2014-07-01 | — | — | US | disclosed |