Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.66 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | CCKAR | P32238 | 3/20 | 0.39 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19155407 | 0.93 | GLP1R (0.62) | GLP1RNOD1FOLH1CCKARCCKBR | |
| SCHEMBL15871502 | 0.92 | GLP1R (0.61) | GLP1RNOD1FOLH1 | |
| SCHEMBL15850016 | 0.91 | GLP1R (0.59) | GLP1RFOLH1 | |
| SCHEMBL24179873 | 0.90 | GLP1R (0.58) | GLP1RNOD1CCKARCCKBR | |
| SCHEMBL15850010 | 0.89 | GLP1R (0.60) | GLP1RNOD1FOLH1EPHX2 | |
| SCHEMBL15849993 | 0.89 | GLP1R (0.60) | GLP1RNOD1FOLH1EPHX2 | |
| SCHEMBL15850000 | 0.89 | GLP1R (0.60) | GLP1RNOD1FOLH1EPHX2 | |
| SCHEMBL16478842 | 0.89 | GLP1R (0.65) | GLP1RFOLH1CCKARCCKBR | |
| SCHEMBL15871463 | 0.89 | GLP1R (0.68) | GLP1RNOD1FOLH1CCKARCCKBR | |
| SCHEMBL16478790 | 0.89 | GLP1R (0.57) | GLP1RNOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765130-B2 | Antagonistic DR3 ligands | NOVO NORDISK A/S (DK) | 2014-07-01 | — | — | US | disclosed |