Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.52 |
| ▸ | GSPT1 | P15170 | 5/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 6/20 | 0.43 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.43 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403675 | 0.89 | CRBN (0.62) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL16556708 | 0.89 | CRBN (0.53) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL15841617 | 0.82 | CRBN (0.62) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL1403628 | 0.82 | CRBN (0.66) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL26148525 | 0.82 | CRBN (0.64) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL26148387 | 0.81 | CRBN (0.63) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL16381535 | 0.80 | CRBN (0.62) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL1413563 | 0.80 | CRBN (0.74) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL13578966 | 0.80 | CRBN (0.62) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL1413399 | 0.80 | CRBN (0.71) | CRBNGSPT1DDB1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749559-A1 | 5-substituted isoindoline compounds | CELGENE CORPORATION (US) | 2014-07-02 | — | — | EP | disclosed |