Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | PIK3R5 | Q8WYR1 | 2/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 2/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850625 | 0.90 | CCNA2 (0.46) | CCNA2CDK2CCNA1ACHEALDH1A1 | |
| SCHEMBL15850651 | 0.90 | CCNA2 (0.45) | CCNA2CDK2CCNA1ALDH1A1MAPT | |
| SCHEMBL12874898 | 0.87 | CCNA2 (0.41) | CCNA2CDK2CCNA1MEN1KMT2A | |
| SCHEMBL12046670 | 0.87 | CCNA2 (0.48) | CCNA2CDK2CCNA1MEN1KMT2A | |
| SCHEMBL12046637 | 0.85 | CCNA2 (0.46) | CCNA2CDK2CCNA1ALDH1A1RAD52 | |
| SCHEMBL12060226 | 0.84 | KDM4E (0.39) | CCNA2CDK2CCNA1KMT2APIK3CD | |
| SCHEMBL12046636 | 0.84 | CCNA2 (0.40) | CCNA2CDK2CCNA1ACHERAD52 | |
| SCHEMBL12046654 | 0.82 | KMT2A (0.37) | CCNA2CDK2CCNA1MEN1KMT2A | |
| SCHEMBL12046651 | 0.81 | CCNA2 (0.44) | CCNA2CDK2CCNA1ALDH1A1MAPT | |
| SCHEMBL1198506 | 0.79 | PDE7A (0.41) | CCNA2CDK2CCNA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459551-B1 | DIHYDROBENZOINDAZOLES | MERCK SHARP & DOHME (NL) | 2014-07-02 | — | — | EP | disclosed |