SCHEMBL15853166

SCHEMBL15853166

CC(C)(C)c1cc(-c2ccc3ccccc3c2)ccc1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
ALOX5 P09917 1/20 0.43
RARB P10826 2/20 0.42
RARG P13631 2/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
GSTP1 P09211 1/20 0.40
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
RARA P10276 1/20 0.39
CA1 P00915 2/20 0.39
CA9 Q16790 2/20 0.39
CA2 P00918 1/20 0.39
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15853144 0.83 ACLY (0.39) ALOX5HSD17B1HSD17B2CYP1A2CYP11B1
SCHEMBL17500066 0.79 CA2 (0.61) ESR1ESR2ALOX5RARBRARG
SCHEMBL3371623 0.77 ESR1 (0.54) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL23479298 0.77 CYP2A6 (0.39) CYP1A2CYP2A6CYP11B1CYP11B2CA2
SCHEMBL23126311 0.76 PTPRC (0.47) ACMSDNPC1ALDH1A1MAPTRAB9A
SCHEMBL23126313 0.76 TAAR1 (0.48) ESR2HSD17B1HSD17B2CYP11B1CYP11B2
SCHEMBL10304848 0.76 ESR1 (0.48) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL5013872 0.73 ESR1 (0.71) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL15902840 0.73 ESR1 (0.71) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL30239998 0.73 ESR1 (0.71) ESR1ESR2ALOX5HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905776-B2 Pyrene-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-27 US disclosed
US-9905776-B2 Pyrene-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-27 US disclosed
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed