SCHEMBL15853232

SCHEMBL15853232

CC(COC(=O)C12CC3CC(CC(C3)C1)C2)(COC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)OCCC(F)(F)C(F)(F)S(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
ATM Q13315 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MAPT P10636 1/20 0.34
PRKCA P17252 1/20 0.33
PKM P14618 1/20 0.33
GAA P10253 1/20 0.32
CYP17A1 P05093 3/20 0.32
CYP19A1 P11511 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15853233 0.99 ALDH1A1 (0.34) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL15842527 0.99 ALDH1A1 (0.34) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL15842526 0.89 ALDH1A1 (0.33) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL8894707 0.87 ALDH1A1 (0.40) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL15853239 0.86 CYP17A1 (0.37) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL4273109 0.86 ALDH1A1 (0.40) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL17066105 0.85 HSD11B1 (0.36) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL15853230 0.85 ALDH1A1 (0.37) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL15853237 0.84 ALDH1A1 (0.36) ALDH1A1KMT2AMEN1ATMNPSR1
SCHEMBL15853225 0.83 ALDH1A1 (0.34) ALDH1A1KMT2AMEN1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9128372-B2 Dendritic compounds, photoresist compositions and methods of making electronic devices ROHM AND HAAS ELECTRONIC MATERIALS LLC 2015-09-08 US disclosed
US-9128372-B2 Dendritic compounds, photoresist compositions and methods of making electronic devices ROHM AND HAAS ELECTRONIC MATERIALS LLC 2015-09-08 US disclosed
US-20140186770-A1 DENDRITIC COMPOUNDS, PHOTORESIST COMPOSITIONS AND METHODS OF MAKING ELECTRONIC DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2014-07-03 US disclosed
US-20140186770-A1 DENDRITIC COMPOUNDS, PHOTORESIST COMPOSITIONS AND METHODS OF MAKING ELECTRONIC DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2014-07-03 US disclosed