Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLI1 | P08151 | 5/20 | 0.59 |
| ▸ | NFKBIA | P25963 | 4/20 | 0.59 |
| ▸ | IDH1 | O75874 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Physalin O SCHEMBL15857092 | 1.00 | GLI1 (0.59) | GLI1NFKBIAIDH1 | |
| Physalin O SCHEMBL30315268 | 1.00 | GLI1 (0.59) | GLI1NFKBIAIDH1 | |
| SCHEMBL29449471 | 0.88 | GLI1 (0.60) | GLI1NFKBIAIDH1 | |
| SCHEMBL15853698 | 0.88 | GLI1 (0.60) | GLI1NFKBIAIDH1 | |
| Physalin A SCHEMBL15853691 | 0.85 | NFKBIA (0.77) | GLI1NFKBIAIDH1 | |
| Physalin A SCHEMBL29449472 | 0.85 | NFKBIA (0.77) | GLI1NFKBIAIDH1 | |
| SCHEMBL31301129 | 0.85 | GLI1 (0.79) | GLI1NFKBIAIDH1 | |
| SCHEMBL31301134 | 0.78 | GLI1 (0.70) | GLI1NFKBIAIDH1 | |
| SCHEMBL15853704 | 0.78 | GLI1 (0.70) | GLI1NFKBIAIDH1 | |
| SCHEMBL15853695 | 0.77 | NFKBIA (0.51) | GLI1NFKBIAIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140187618-A1 | COMPOSITIONS, METHODS AND KITS USING FOR INDUCING OR ENHANCING NEUROGENESIS IN CELLS AND TISSUE | Biocrescentia, LLC (US) | 2014-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187618-A1 | COMPOSITIONS, METHODS AND KITS USING FOR INDUCING OR ENHANCING NEUROGENESIS IN CELLS AND TISSUE | DCX, CHAT, ACHE | GLI1 2150/4885NFKBIA 2228/4885IDH1 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.