Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17219483 | 0.99 | KMT2A (0.47) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15854220 | 0.88 | KMT2A (0.51) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14490544 | 0.87 | HDAC3 (0.55) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL17219703 | 0.86 | KMT2A (0.50) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL17219701 | 0.86 | KMT2A (0.50) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30071662 | 0.83 | RAB9A (0.50) | HDAC8HDAC6LMNASMN1; SMN2GAA | |
| SCHEMBL5436269 | 0.83 | RAB9A (0.50) | HDAC8HDAC6LMNASMN1; SMN2GAA | |
| SCHEMBL15854253 | 0.83 | SMN1; SMN2 (0.52) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5436265 | 0.83 | RAB9A (0.50) | HDAC8HDAC6LMNASMN1; SMN2GAA | |
| SCHEMBL1711277 | 0.83 | PTPN2 (0.46) | KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540338-B2 | Substituted cinnamic acid amides for treating pain | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-20150322024-A1 | Cinnamic Acid Amide Derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-2940003-A1 | CINNAMIC ACID AMIDE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
| WO-2014104272-A1 | CINNAMIC ACID AMIDE DERIVATIVE | 日本臓器製薬株式会社 (JP) | 2014-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322024-A1 | Cinnamic Acid Amide Derivative | OPRL1, TRPV1, TRPA1 | KMT2A 1648/4885HDAC3 71/4885HDAC4 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.