SCHEMBL1585548

SCHEMBL1585548

CCCCCCCCCC[CH]N

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
THRB P10828 1/20 0.50
FAAH O00519 3/20 0.46
TRPV1 Q8NER1 1/20 0.46
DNM1 Q05193 7/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.45
EPHX1 P07099 1/20 0.45
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
SOAT1 P35610 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4755751 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL1948712 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL2031870 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4754038 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755758 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755731 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL2153463 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755755 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4757186 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4757192 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3234061-A1 NANO-INHIBITORS Total SA (FR) 2017-10-25 EP claimed
WO-2016097492-A1 NANO-INHIBITORS TOTAL SA (FR) 2016-06-23 WO claimed
WO-2015197860-A2 NOVEL THAPSIGARGIN ANALOGUES AND METHODS OF PREPARING THEM UNIVERSITY OF COPENHAGEN (DK) 2015-12-30 WO claimed
EP-3595797-A1 METHOD OF DEPLETING AN ORGANOSILICON COMPONENT IN A MIXTURE USING A SORBENT COPOLYMER AND APPARATUS FOR PRACTICING THE METHOD Dow Silicones Corporation (US) 2020-01-22 EP disclosed
EP-3491096-A2 GEL-TYPE THERMAL INTERFACE MATERIAL Honeywell International Inc. (US) 2019-06-05 EP disclosed
EP-3463618-A1 METHOD OF DEPLETING A VOLATILE COMPONENT IN A MIXTURE USING A CROSSLINKED ELASTOMER SORBENT AND APPARATUS FOR PRACTICING THE METHOD Dow Corning Corporation (US) 2019-04-10 EP disclosed
WO-2018169681-A1 METHOD OF DEPLETING AN ORGANOSILICON COMPONENT IN A MIXTURE USING A SORBENT COPOLYMER AND APPARATUS FOR PRACTICING THE METHOD DOW SILICONES CORPORATION (US) 2018-09-20 WO disclosed
WO-2018022288-A2 GEL-TYPE THERMAL INTERFACE MATERIAL HONEYWELL INTERNATIONAL INC. (US) 2018-02-01 WO disclosed
EP-3234061-A1 NANO-INHIBITORS Total SA (FR) 2017-10-25 EP disclosed
EP-2490663-B1 SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL DOW CORNING (US) 2017-09-20 EP disclosed
EP-3155036-A2 METHOD OF FORMING AN ORGANOSILICON PRODUCT USING A MEMBRANE CONTACTOR TO REACT A GAS AND LIQUID Dow Corning Corporation (US) 2017-04-19 EP disclosed
CN-101321529-B Diaryl aether derivant as antineoplastic agent OTSUKA PHARMA CO LTD 2012-09-05 CN disclosed
EP-2490663-A2 SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL Dow Corning Corporation (US) 2012-08-29 EP disclosed
EP-2491065-A1 HYDROPHILICALLY-MODIFIED SILICONE COMPOSITIONS Dow Corning Corporation (US) 2012-08-29 EP disclosed
WO-2011109174-A1 SURFACE -MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES DOW CORNING CORPORATION (US) 2011-09-09 WO disclosed
WO-2011103291-A1 SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS DOW CORNING CORPORATION (US) 2011-08-25 WO disclosed
WO-2011049919-A1 HYDROPHILICALLY-MODIFIED SILICONE COMPOSITIONS DOW CORNING CORPORATION (US) 2011-04-28 WO disclosed
WO-2011049896-A2 SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL DOW CORNING CORPORATION (US) 2011-04-28 WO disclosed
EP-2004737-A1 DELIVERY DEVICE Dow Corning Corporation (US) 2008-12-24 EP disclosed
WO-2007118816-A1 DELIVERY DEVICE DOW CORNING CORPORATION (US) 2007-10-25 WO disclosed