SCHEMBL1948712

SCHEMBL1948712

CCCCCCCCCCCCCCC[CH]N

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
THRB P10828 1/20 0.50
FAAH O00519 3/20 0.46
TRPV1 Q8NER1 1/20 0.46
DNM1 Q05193 7/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.45
EPHX1 P07099 1/20 0.45
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
SOAT1 P35610 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4755751 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL1585548 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL2031870 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4754038 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755758 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755731 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL2153463 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755755 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4757186 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4757192 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10758492-B2 Two-dimensional polymeric structures and method for producing thereof Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2020-09-01 US disclosed
CN-107815670-B Barrier coating for selective metallization 罗门哈斯电子材料有限责任公司 2020-03-10 CN disclosed
US-20170258737-A1 TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2017-09-14 US disclosed
EP-3193846-A1 TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2017-07-26 EP disclosed
WO-2016042484-A1 TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2016-03-24 WO disclosed
US-9107814-B2 Micelle composition of polymer and passenger drug WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-08-18 US disclosed
US-20120309780-A1 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-12-06 US disclosed
EP-2516508-A2 AMPHIPHILIC POLYMER FUNCTIONALISED BY METHIONINE Flamel Technologies (FR) 2012-10-31 EP disclosed
US-8173167-B2 Micelle composition of polymer and passenger drug WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-05-08 US disclosed
WO-2011077402-A2 AMPHIPHILIC POLYMER FUNCTIONALISED BY METHIONINE FLAMEL TECHNOLOGIES (FR) 2011-06-30 WO disclosed
US-20110150837-A1 Amphiphilic polymer functionalized by methionine FLAMEL TECHNOLOGIES (FR) 2011-06-23 US disclosed
US-20110136975-A1 MONOMER MIXTURE, POLYMER, COATING MEANS AND METHOD FOR PRODUCING A COATING EVONIK ROEHM GMBH (DE) 2011-06-09 US disclosed
WO-2008110612-A2 NOVEL COMPOUNDS AND LUBRICATING COMPOSITIONS COMPRISING THE SAME SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-09-18 WO disclosed
WO-2006110862-A9 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RES FOUND (US) 2008-08-07 WO disclosed
EP-1871343-A2 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-01-02 EP disclosed
US-20060251710-A1 Micelle composition of polymer and passenger drug NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-11-09 US disclosed
WO-2006110862-A2 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-10-19 WO disclosed
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US disclosed
US-4631272-A N-acylated 1-alkylamino-1-deoxy-ketose derivatives, a process for their preparation and their use BAYER AKTIENGESELLSCHAFT (DE) 1986-12-23 US disclosed
EP-0152856-A2 N-acylated 1-alkylamimo-1-desoxy ketose derivatives, method for their preparation and use BAYER AG (DE) 1985-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170258737-A1 TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF MLEC, EPCAM, VIM TSHR 4159/4885THRB 3177/4885FAAH 4885/4885
US-20110150837-A1 Amphiphilic polymer functionalized by methionine MTR, LNPEP, METAP1 TSHR 3037/4885THRB 2484/4885FAAH 1755/4885
US-10758492-B2 Two-dimensional polymeric structures and method for producing thereof MLEC, EPCAM, VIM TSHR 4159/4885THRB 3177/4885FAAH 4885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.