Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755751 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL1585548 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL1948712 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2031870 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL4754038 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL4755758 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL4755731 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2153463 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL4755755 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL4757192 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110612-A2 | NOVEL COMPOUNDS AND LUBRICATING COMPOSITIONS COMPRISING THE SAME | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2008-09-18 | — | — | WO | disclosed |
| US-6949281-B1 | Varnish composition and liquid-crystal display element | CHISSO CORPORATION (JP) | 2005-09-27 | — | — | US | disclosed |