Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18388499 | 0.92 | ALDH1A1 (0.38) | MAPTRAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL24369350 | 0.91 | ROCK2 (0.34) | MAPTLMNA | |
| SCHEMBL12863863 | 0.91 | ALDH1A1 (0.41) | RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5363264 | 0.85 | EPHX2 (0.37) | RAB9AALDH1A1KMT2AACACBLMNA | |
| SCHEMBL12251471 | 0.80 | MIF (0.37) | MAPTRAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL10321962 | 0.79 | ACACB (0.36) | MAPTNPSR1GAAACACBLMNA | |
| SCHEMBL5370039 | 0.79 | ACACB (0.36) | MAPTNPSR1GAAACACBLMNA | |
| SCHEMBL2986183 | 0.79 | ACACB (0.36) | MAPTNPSR1GAAACACBLMNA | |
| SCHEMBL2990263 | 0.79 | ACACB (0.36) | MAPTNPSR1GAAACACBLMNA | |
| Propane SCHEMBL28113027 | 0.77 | TSHR (0.39) | MAPTALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2769972-B1 | Novel organoleptic compound | INT FLAVORS & FRAGRANCES INC (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2769972-B1 | Novel organoleptic compound | INT FLAVORS & FRAGRANCES INC (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2769971-B1 | Novel Organoleptic Compound | INT FLAVORS & FRAGRANCES INC (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2769971-B1 | Novel Organoleptic Compound | INT FLAVORS & FRAGRANCES INC (US) | 2015-09-16 | — | — | EP | disclosed |
| CN-104016860-A | Novel Organoleptic Compound | INT FLAVORS & FRAGRANCES INC | 2014-09-03 | — | — | CN | disclosed |
| EP-2769971-A1 | Novel Organoleptic Compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-08-27 | — | — | EP | disclosed |
| EP-2769971-A1 | Novel Organoleptic Compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-08-27 | — | — | EP | disclosed |
| EP-2769972-A1 | Novel organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-08-27 | — | — | EP | disclosed |
| EP-2769972-A1 | Novel organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-08-27 | — | — | EP | disclosed |
| CN-104003882-A | Novel organoleptic compound | INT FLAVORS & FRAGRANCES INC | 2014-08-27 | — | — | CN | disclosed |
| US-8785677-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785677-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785677-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8772533-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772533-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772533-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-08 | — | — | US | disclosed |