SCHEMBL15856424

SCHEMBL15856424

CN(c1ccccc1F)c1ccc(-c2cccc(-c3ccccc3)c2)c(-c2ccccc2)c1F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACLY P53396 2/20 0.34
PTGS2 P35354 2/20 0.32
PTGS1 P23219 1/20 0.31
SLC6A9 P48067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856407 0.95 PTGS2 (0.36) ACLYPTGS2PTGS1SLC6A9
SCHEMBL15856455 0.90 AKR1C3 (0.38) ACLYPTGS2PTGS1
SCHEMBL15856493 0.90 PTGS2 (0.36) ACLYPTGS2PTGS1
SCHEMBL15856545 0.90 PTGS2 (0.36) ACLYPTGS2PTGS1
SCHEMBL15856452 0.90 PTGS2 (0.34) ACLYPTGS2PTGS1
SCHEMBL15856449 0.88 AKR1C3 (0.36) SLC6A9
SCHEMBL15856344 0.86 AKR1C3 (0.36) ACLYPTGS2PTGS1
SCHEMBL15856347 0.86 AKR1C3 (0.36) ACLYPTGS2PTGS1
SCHEMBL15856439 0.86 SLC6A9 (0.35) ACLYSLC6A9
SCHEMBL15856483 0.85 AKR1C3 (0.38) ACLYPTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed