SCHEMBL15856465

SCHEMBL15856465

Cc1cc(F)ccc1-c1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA9 Q16790 3/20 0.51
CYP2A6 P11509 4/20 0.45
ALDH1A1 P00352 2/20 0.45
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
FABP1 P07148 1/20 0.43
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
CYP1A2 P05177 4/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PPARG P37231 1/20 0.39
TSHR P16473 1/20 0.38
DHFR P00374 1/20 0.38
GPR3 P46089 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856460 0.86 CYP2A6 (0.45) CA12CA1CA2CA9CYP2A6
SCHEMBL6548332 0.81 CA12 (0.54) CA12CA1CA2CA9CYP2A6
SCHEMBL19975718 0.81 CYP1A2 (0.52) CYP2A6ALDH1A1AKR1C3AKR1C2CYP1A2
SCHEMBL29549050 0.81 CYP1A2 (0.52) CYP2A6ALDH1A1AKR1C3AKR1C2CYP1A2
SCHEMBL3756908 0.81 S1PR1 (0.46) CYP2A6ALDH1A1FABP1CYP1A2HPGD
SCHEMBL17038887 0.79 FABP1 (0.40) CYP2A6FABP1CYP1A2HSD17B10GPR3
SCHEMBL2996863 0.78 CYP2A6 (0.65) CA12CA1CA2CA9CYP2A6
SCHEMBL15853133 0.78 AKR1C3 (0.42) CA12CA1CA2CA9CYP2A6
SCHEMBL14039912 0.78 PDE3B (0.44) CA1CA2CA9PPARGGPR3
SCHEMBL25053990 0.78 ALDH1A1 (0.42) CA12CA1CA2CA9CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed