SCHEMBL2996863

SCHEMBL2996863

Cc1ccccc1-c1cccc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.65
ALDH1A1 P00352 5/20 0.65
CYP1A2 P05177 4/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.50
CA12 O43570 3/20 0.49
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA9 Q16790 3/20 0.49
TSHR P16473 2/20 0.48
DHFR P00374 1/20 0.46
BRD4 O60885 1/20 0.46
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 2/20 0.43
ENPP3 O14638 1/20 0.43
ENPP1 P22413 1/20 0.43
ADORA2A P29274 1/20 0.43
KIF11 P52732 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23989058 0.87 ALDH1A1 (0.50) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL30159344 0.86 CYP2A6 (0.60) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL6548329 0.86 CYP2A6 (0.60) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL15856404 0.85 CYP2A6 (0.58) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL29350007 0.84 ALDH1A1 (0.59) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL25302086 0.84 ALDH1A1 (0.59) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL27953 0.84 ALDH1A1 (0.59) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL1132842 0.84 CYP2A6 (0.62) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL29801671 0.84 CYP2A6 (0.62) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL3747187 0.84 CYP2A6 (0.62) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7485754-B2 Efficient method for preparing 3-aryloxy-3-arylpropylamines and their optical stereoisomers APOTEX PHARMACHEM INC. (CA) 2009-02-03 US claimed
CN-118339237-B Reversible thermochromic microcapsule pigments 株式会社百乐 2026-05-12 CN disclosed
CN-115551352-B Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-11-08 CN disclosed
CN-115515426-B Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-11-08 CN disclosed
CN-118496197-A Substituted thiophenecarboxamides, thiophenecarboxylic acids and derivatives thereof 拜耳公司 2024-08-16 CN disclosed
CN-118339237-A Reversible thermochromic microcapsule pigments 株式会社百乐 2024-07-12 CN disclosed
CN-114364663-B Substituted thiophenecarboxamides and derivatives thereof as microbiocides 拜耳公司 2024-07-05 CN disclosed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 CN disclosed
CN-112601744-B Substituted thiophenecarboxamides and analogues as antibacterial agents 拜耳公司 2024-03-29 CN disclosed
CN-112638894-B Substituted thiophenecarboxamides and analogues as antibacterial agents 拜耳公司 2024-03-29 CN disclosed
US-4798685-A Production of base-type conducting polymers LOCKHEED CORPORATION (US) 1989-01-17 US disclosed
WO-1988006064-A1 ELECTRONIC DEVICE FABRICATION BY SELECTIVE DOPING OF A NON-CONDUCTIVE POLYMER LOCKHEED CORPORATION (US) 1988-08-25 WO disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
US-4601588-A COMPONENT WHICH MELTS AT A PORESCRIBED TEMPERATURE AND CHANGES COLOR, INDICATING FRESHNESS OF FROZEN FOODS MATSUMOTO KOSAN KABUSHIKI KAISHA (JP) 1986-07-22 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4054533-A DIPHENYL ETHER, 2- OR 4-BIPHENYLYLPHENYL ETHER, TRIPHENYLPHENOL THE DOW CHEMICAL COMPANY (US) 1977-10-18 US disclosed
US-3979324-A BENZYLNAPHTHALENE COMPOUND MONSANTO COMPANY (US) 1976-09-07 US disclosed
US-3936473-A COPPER OR NOBLE METAL SALT, OXYGEN AND ORGANIC ACID CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-03 US disclosed