Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585822 | 0.89 | EGLN1 (0.47) | EGLN1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL1586015 | 0.87 | EGLN1 (0.45) | EGLN1LMNAUSP2TSHRSMN1; SMN2 | |
| SCHEMBL1586272 | 0.86 | EGLN1 (0.46) | EGLN1ALDH1A1HTTHIF1ABBOX1 | |
| SCHEMBL1585687 | 0.86 | EGLN1 (0.56) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1585620 | 0.84 | EGLN1 (0.48) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL1585869 | 0.83 | EGLN1 (0.47) | EGLN1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1586363 | 0.82 | EGLN1 (0.50) | EGLN1HIF1AEGLN3EGLN2 | |
| SCHEMBL1585836 | 0.82 | EGLN1 (0.48) | EGLN1ALDH1A1NPSR1HIF1ABBOX1 | |
| SCHEMBL1585642 | 0.82 | EGLN1 (0.50) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1585697 | 0.82 | EGLN1 (0.48) | EGLN1HIF1ABBOX1ASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | claimed |