Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585836 | 0.90 | EGLN1 (0.48) | EGLN1EGLN3EGLN2ALDH1A1MEN1 | |
| SCHEMBL1585687 | 0.87 | EGLN1 (0.56) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1586489 | 0.86 | EGLN1 (0.45) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1585822 | 0.86 | EGLN1 (0.47) | EGLN1EGLN3SMN1; SMN2LMNAHTT | |
| SCHEMBL1586015 | 0.84 | EGLN1 (0.45) | EGLN1SMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL1585642 | 0.84 | EGLN1 (0.50) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1586363 | 0.84 | EGLN1 (0.50) | EGLN1EGLN3EGLN2MEN1MAPT | |
| SCHEMBL1585880 | 0.84 | EGLN3 (0.46) | EGLN1EGLN3EGLN2LMNAMAPT | |
| SCHEMBL1586450 | 0.83 | EGLN1 (0.44) | EGLN1EGLN3EGLN2SMN1; SMN2LMNA | |
| SCHEMBL1585982 | 0.83 | ALDH1A1 (0.46) | EGLN1EGLN3EGLN2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |