Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585886 | 1.00 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1586380 | 0.88 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1586384 | 0.88 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1586360 | 0.86 | KDM4E (0.43) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1586361 | 0.86 | KDM4E (0.43) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1585769 | 0.83 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1585770 | 0.83 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1585958 | 0.82 | OGFRL1 (0.46) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1585956 | 0.82 | OGFRL1 (0.46) | L3MBTL1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1586308 | 0.81 | HIF1A (0.55) | MEN1KMT2AEGLN1BBOX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |