Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859414 | 1.00 | CTSS (0.42) | CTSSCTSL | |
| SCHEMBL15064330 | 0.92 | CTSS (0.40) | CTSS | |
| SCHEMBL12070307 | 0.86 | HDAC4 (0.41) | CTSSCTSL | |
| SCHEMBL15859407 | 0.80 | CTSL (0.30) | CTSL | |
| SCHEMBL15859406 | 0.80 | CTSL (0.30) | CTSL | |
| SCHEMBL15064327 | 0.79 | CTSS (0.34) | CTSS | |
| SCHEMBL15086641 | 0.75 | HDAC4 (0.41) | CTSSCTSL | |
| SCHEMBL15064628 | 0.72 | — | — | |
| SCHEMBL12069219 | 0.69 | CTSS (0.55) | CTSS | |
| SCHEMBL28364368 | 0.67 | GRN (0.39) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582660-B1 | NEW CATHEPSIN S PROTEASE INHIBITORS, USEFUL IN THE TREATMENT OF E.G. AUTOIMMUNE DISORDERS, ALLERGY AND CHRONIC PAIN CONDITIONS | MEDIVIR UK LTD (GB) | 2015-07-22 | — | — | EP | disclosed |
| EP-2752404-A1 | Cysteine protease inhibitors | Medivir UK Ltd (GB) | 2014-07-09 | — | — | EP | disclosed |