SCHEMBL158652

SCHEMBL158652

NC(CCCP(=O)(O)O)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 1/20 0.66
GLUL P15104 1/20 0.60
ALDH1A1 P00352 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
OTC P00480 1/20 0.56
GSR P00390 1/20 0.54
ENPEP Q07075 1/20 0.53
GRM8 O00222 1/20 0.53
GRM6 O15303 1/20 0.53
GRM7 Q14831 1/20 0.53
GRM4 Q14833 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1662220 1.00 BHMT (0.66) BHMTGLULALDH1A1TDP1OTC
SCHEMBL158653 1.00 BHMT (0.66) BHMTGLULALDH1A1TDP1OTC
SCHEMBL1978027 0.94 BHMT (0.69) BHMTGLULTDP1OTCGSR
SCHEMBL12648651 0.94 BHMT (0.69) BHMTGLULTDP1OTCGSR
SCHEMBL13997086 0.94 BHMT (0.69) BHMTGLULTDP1OTCGSR
Water SCHEMBL21747431 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
Hydrochloric Acid SCHEMBL21747394 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
SCHEMBL21747440 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
SCHEMBL21747426 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
Water SCHEMBL21747391 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2443 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12589097-B2 Apilimod compositions and methods of use OrphAl Therapeutics Inc. (US) 2026-03-31 US claimed
EP-4623932-A1 AGENT FOR ALLEVIATING CLOZAPINE-INDUCED SIALORRHEA National University Corporation Chiba University (JP) 2025-10-01 EP claimed
CN-118853834-B Detection system and detection method for tobramycin based on CRISPR-Cas12a and hybridization chain reaction 江苏第二师范学院 2025-06-24 CN claimed
WO-2025065271-A1 METHODS AND DEVICES FOR TREATING DEPRESSION Liangzhu Laboratory (CN) 2025-04-03 WO claimed
WO-2025030033-A1 APILIMOD COMPOSITIONS AND METHODS OF USE ORPHAI THERAPEUTICS INC. (US) 2025-02-06 WO claimed
US-12194201-B2 Silica nanoparticle doped conductive polymer University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-01-14 US claimed
EP-4475953-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN, Fikret (TR) 2024-12-18 EP claimed
CN-119095622-A NMDAR antagonists prevent aging and aging-related conditions and diseases by increasing 20S proteasome activity 菲克雷特·萨欣 2024-12-06 CN claimed
CN-118853834-A Detection system and detection method for tobramycin based on CRISPR-Cas12a and hybridization chain reaction 江苏第二师范学院 2024-10-29 CN claimed
CN-118684620-A Betel nut alkaloid and preparation method and application thereof 暨南大学 2024-09-24 CN claimed
EP-0797442-A4 TREATMENT OF OPTIC NEURITIS MASSACHUSETTS EYE & EAR INFIRM (US) 1998-04-15 EP claimed
EP-0797442-A1 TREATMENT OF OPTIC NEURITIS MASSACHUSETTS EYE & EAR INFIRMARY (US) 1997-10-01 EP claimed
EP-0778023-A1 Neuroprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1997-06-11 EP claimed
WO-1996000073-A1 TREATMENT OF OPTIC NEURITIS MASSACHUSETTS EYE AND EAR INFIRMARY (US) 1996-01-04 WO claimed
EP-0557290-A1 TREATMENT OF AIDS DEMENTIA, MYELOPATHY, PERIPHERAL NEUROPATHY, AND VISION LOSS The Children's Medical Center Corporation (US) 1993-09-01 EP claimed
EP-0557290-A4 TREATMENT OF AIDS DEMENTIA, MYELOPATHY, PERIPHERAL NEUROPATHY, AND VISION LOSS. CHILDRENS MEDICAL CENTER (US) 1993-07-14 EP claimed
WO-1992003137-A1 TREATMENT OF AIDS DEMENTIA, MYELOPATHY, PERIPHERAL NEUROPATHY, AND VISION LOSS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1992-03-05 WO claimed
EP-0432994-A2 Excitatory amino acid antagonists as anti-emetic drugs Olney, John William (US) 1991-06-19 EP claimed
US-4994446-A Drug system RAMOT - UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) 1991-02-19 US claimed
WO-1988007851-A1 LIPOSOME ENTRAPPED N-METHYL-D-ASPARTATE RECEPTOR BLOCKERS INNOVATIVE THERAPEUTICS CORPORATION (US) 1988-10-20 WO claimed