SCHEMBL1662220

SCHEMBL1662220

N[C@@H](CCCP(=O)(O)O)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 1/20 0.66
GLUL P15104 1/20 0.60
ALDH1A1 P00352 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
OTC P00480 1/20 0.56
GSR P00390 1/20 0.54
ENPEP Q07075 1/20 0.53
GRM8 O00222 1/20 0.53
GRM6 O15303 1/20 0.53
GRM7 Q14831 1/20 0.53
GRM4 Q14833 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158652 1.00 BHMT (0.66) BHMTGLULALDH1A1TDP1OTC
SCHEMBL158653 1.00 BHMT (0.66) BHMTGLULALDH1A1TDP1OTC
SCHEMBL1978027 0.94 BHMT (0.69) BHMTGLULTDP1OTCGSR
SCHEMBL12648651 0.94 BHMT (0.69) BHMTGLULTDP1OTCGSR
SCHEMBL13997086 0.94 BHMT (0.69) BHMTGLULTDP1OTCGSR
Water SCHEMBL21747431 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
Hydrochloric Acid SCHEMBL21747394 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
SCHEMBL21747440 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
SCHEMBL21747426 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR
Water SCHEMBL21747391 0.92 BHMT (0.67) BHMTGLULTDP1OTCGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695412-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 EP disclosed
US-12357635-B2 Nanocarriers and their processing for diagnostics and therapeutics RHODE ISLAND HOSPITAL (US) 2025-07-15 US disclosed
EP-3551182-B1 TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -)AN ALGESIC FOR THE TREATMENT OF CHRONIC PAIN TOPICAL INNOVATIONS B V (NL) 2025-03-19 EP disclosed
US-20240344041-A1 ARTIFICIAL PROTEIN TO RESTORE SYNAPTIC FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-10-17 US disclosed
WO-2024216030-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-10-17 WO disclosed
US-20240156853-A1 IN VITRO AND IN VIVO INTRACELLULAR DELIVERY OF SIRNA VIA SELF-ASSEMBLED NANOPIECES RHODE ISLAND HOSPITAL 2024-05-16 US disclosed
EP-3716957-B1 STEROIDAL COMPOUNDS FOR TREATMENT OF MENTAL AND NEUROLOGICAL DISORDERS USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2023-07-19 EP disclosed
US-11701379-B2 In vitro and in vivo intracellular delivery of siRNA via self-assembled nanopieces RHODE ISLAND HOSPITAL (US) 2023-07-18 US disclosed
US-20230142111-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-05-11 US disclosed
US-20220193096-A1 INHIBITORS OF NCCA-ATP CHANNELS FOR THERAPY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2022-06-23 US disclosed
EP-1861104-A2 IMPROVED GACYCLIDINE FORMULATIONS Neurosystec Corporation (US) 2007-12-05 EP disclosed
EP-1861161-A2 APPARATUS AND METHOD FOR DELIVERING THERAPEUTIC AND/OR OTHER AGENTS TO THE INNER EAR AND TO OTHER TISSUES Neurosystec Corporation (US) 2007-12-05 EP disclosed
US-20070078082-A1 Methods and compositions to treat glycosaminoglycan-associated molecular interactions NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-04-05 US disclosed
US-20060264897-A1 Apparatus and method for delivering therapeutic and/or other agents to the inner ear and to other tissues NEUROSYSTEC CORPORATION (US) 2006-11-23 US disclosed
US-20060205789-A1 Gacyclidine formulations NEUROSYSTEC CORPORATION (US) 2006-09-14 US disclosed
WO-2006096518-A2 IMPROVED GACYCLIDINE FORMULATIONS NEUROSYSTEC CORPORATION (US) 2006-09-14 WO disclosed
WO-2006079055-A2 APPARATUS AND METHOD FOR DELIVERING THERAPEUTIC AND/OR OTHER AGENTS TO THE INNER EAR AND TO OTHER TISSUES NEUROSYSTEC CORPORATION (US) 2006-07-27 WO disclosed
CN-1672055-A Heterologous stimulus-gated ion channels and methods of using same SLOAN KETTERING INST CANCER (US) 2005-09-21 CN disclosed
US-6616846-B2 Extraction of phosphonates MDS (CANADA) INC. (CA) 2003-09-09 US disclosed
US-20030042204-A1 Extraction of phosphonates MDS (CANADA) INC. (CA) 2003-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12357635-B2 Nanocarriers and their processing for diagnostics and therapeutics SYVN1, SSB, TNF BHMT 3914/4885GLUL 3952/4885ALDH1A1 2015/4885
US-11701379-B2 In vitro and in vivo intracellular delivery of siRNA via self-assembled nanopieces NFATC1, TRAF6, UACA BHMT 3944/4885GLUL 3804/4885ALDH1A1 3763/4885
US-20230142111-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS GRIN2D, GRIN2A, GRIN2C BHMT 350/4885GLUL 657/4885ALDH1A1 1764/4885
US-20070078082-A1 Methods and compositions to treat glycosaminoglycan-associated molecular interactions HPSE, CD44, CSGALNACT1 BHMT 3847/4885GLUL 1997/4885ALDH1A1 2097/4885
US-20240156853-A1 IN VITRO AND IN VIVO INTRACELLULAR DELIVERY OF SIRNA VIA SELF-ASSEMBLED NANOPIECES NFATC1, TRAF6, UACA BHMT 3944/4885GLUL 3804/4885ALDH1A1 3763/4885
US-20060205789-A1 Gacyclidine formulations DCTD, TYMP, TYMS BHMT 1433/4885GLUL 170/4885ALDH1A1 1839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.