Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131138 | 0.98 | TDP1 (0.58) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL15865003 | 0.95 | TDP1 (0.53) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL16684723 | 0.92 | TDP1 (0.56) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL216569 | 0.90 | TDP1 (0.73) | TDP1ALDH1A1TSHRLMNAESR1 | |
| SCHEMBL12938315 | 0.89 | ESR1 (0.49) | TDP1ALDH1A1TSHRESR1CYP3A4 | |
| SCHEMBL276086 | 0.87 | SERPINE1 (0.50) | TDP1ESR1 | |
| SCHEMBL6067577 | 0.87 | ESR1 (0.47) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL218011 | 0.85 | TDP1 (0.56) | TDP1NPC1RAB9ATSHRLMNA | |
| SCHEMBL29378202 | 0.84 | TSHR (0.45) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL218327 | 0.84 | TSHR (0.45) | TDP1ALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014107476-A1 | ACID-STRIPPABLE SILICON-CONTAINING ANTIREFLECTIVE COATING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-10 | — | — | WO | disclosed |