SCHEMBL216569

SCHEMBL216569

C=COCCCCOC(=O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.73
LMNA P02545 1/20 0.54
MAPK1 P28482 2/20 0.47
HIF1A Q16665 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
TSHR P16473 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
CNR2 P34972 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1131138 0.91 TDP1 (0.58) TDP1LMNAMAPK1SLC6A2ALDH1A1
SCHEMBL2978166 0.90 TDP1 (0.61) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL15865271 0.90 TDP1 (0.56) TDP1LMNAMAPK1SLC6A2ALDH1A1
SCHEMBL218011 0.89 TDP1 (0.56) TDP1LMNASMN1; SMN2TSHR
SCHEMBL16684723 0.89 TDP1 (0.56) TDP1LMNAMAPK1ALDH1A1SMN1; SMN2
SCHEMBL15865003 0.88 TDP1 (0.53) TDP1LMNAMAPK1SLC6A2SLC6A3
SCHEMBL2192154 0.88 TDP1 (0.56) TDP1LMNAKMT2ACNR2
SCHEMBL29975539 0.88 TDP1 (0.56) TDP1LMNAKMT2ACNR2
SCHEMBL12879054 0.87 TDP1 (0.54) TDP1LMNAKMT2ASMN1; SMN2
SCHEMBL223441 0.86 TDP1 (1.00) TDP1LMNAMAPK1HIF1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100242790-A1 CATIONICALLY AND HYBRID CURABLE UV GELS XEROX CORPORATION (US) 2010-09-30 US claimed
EP-2233541-A1 Cationically and hybrid curable UV gels Xerox Corporation (US) 2010-09-29 EP claimed
EP-0861453-A1 MATRIX COMPOUNDS FOR FORMING OPTICAL FIBER RIBBONS Lightguide Materials, Inc. (US) 1998-09-02 EP claimed
WO-1997018493-A1 MATRIX COMPOUNDS FOR FORMING OPTICAL FIBER RIBBONS LIGHTGUIDE MATERIALS, INC. (US) 1997-05-22 WO claimed
EP-4565378-B1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-05-06 EP disclosed
US-12616995-B2 Methods for producing overt security features exhibiting one or more indicia SICPA HOLDING SA (CH) 2026-05-05 US disclosed
EP-4352175-B1 HYBRID UV-LED RADIATION CURABLE PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS SICPA HOLDING SA (CH) 2026-02-25 EP disclosed
US-12535735-B2 Modified thioxanthone photoinitiators LINTFIELD LIMITED (GB) 2026-01-27 US disclosed
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-01-15 US disclosed
US-12515470-B2 UV-Vis radiation curable security inks SICPA HOLDING SA (CH) 2026-01-06 US disclosed
EP-4433547-B1 METHODS FOR PRODUCING OVERT SECURITY FEATURES EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2025-12-24 EP disclosed
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition LINTFIELD LIMITED (GB) 2025-08-26 US disclosed
WO-1997018493-A1 MATRIX COMPOUNDS FOR FORMING OPTICAL FIBER RIBBONS LIGHTGUIDE MATERIALS, INC. (US) 1997-05-22 WO disclosed
EP-0549588-B1 VINYL ETHER BASED OPTICAL FIBER COATINGS ALLIED SIGNAL INC (US) 1995-08-16 EP disclosed
EP-0483750-B1 Fluorine-containing copolymer and curable composition containing the same DAIKIN IND LTD (JP) 1994-10-05 EP disclosed
EP-0549588-A1 VINYL ETHER BASED OPTICAL FIBER COATINGS. ALLIED SIGNAL INC (US) 1993-07-07 EP disclosed
US-5142011-A Films, coatings, sealants; solvent solubility, gloss, weatherability DAIKIN INDUSTRIES, LTD. (JP) 1992-08-25 US disclosed
US-5139872-A Polyetherurethanes and polyesterurethanes endcapped with hydroxyvinyl ethers reacted with vinyl ether terminated ester or vinyl ether ALLIED-SIGNAL INC. (US) 1992-08-18 US disclosed
EP-0483750-A1 Fluorine-containing copolymer and curable composition containing the same DAIKIN INDUSTRIES, LIMITED (JP) 1992-05-06 EP disclosed
WO-1992004388-A1 VINYL ETHER BASED OPTICAL FIBER COATINGS ALLIED-SIGNAL INC. (US) 1992-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition TPMT, TST, PPOX TDP1 235/4885LMNA 1218/4885MAPK1 4870/4885
US-12535735-B2 Modified thioxanthone photoinitiators FTO, UGT1A6, TPMT TDP1 1322/4885LMNA 1247/4885MAPK1 2495/4885
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA IK, TEX10, INCENP TDP1 1958/4885LMNA 77/4885MAPK1 1758/4885
US-12616995-B2 Methods for producing overt security features exhibiting one or more indicia ATG4B, TPM4, ATG4A TDP1 2099/4885LMNA 1850/4885MAPK1 3659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.