Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15843546 | 0.91 | TSHR (0.50) | TSHRTDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL15843547 | 0.91 | TSHR (0.50) | TSHRTDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL15843162 | 0.89 | ALDH1A1 (0.49) | TSHRL3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL15843161 | 0.89 | ALDH1A1 (0.49) | TSHRL3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL15843802 | 0.86 | TSHR (0.51) | TSHRTDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL15843801 | 0.86 | TSHR (0.51) | TSHRTDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL15843637 | 0.85 | TSHR (0.53) | TSHRFAAHALDH1A1LMNACYP3A4 | |
| SCHEMBL15843638 | 0.85 | TSHR (0.53) | TSHRFAAHALDH1A1LMNACYP3A4 | |
| SCHEMBL15843503 | 0.85 | TSHR (0.53) | TSHRFAAHALDH1A1LMNACYP3A4 | |
| SCHEMBL15843504 | 0.85 | TSHR (0.53) | TSHRFAAHALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014107447-A1 | FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2014-07-10 | — | — | WO | claimed |