Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15866002 | 0.91 | KCNA3 (0.54) | KCNA3HTR1BHTR1DTAAR1ALDH1A1 | |
| SCHEMBL9944281 | 0.81 | KCNA3 (0.47) | KCNA3PKMHTR1BHTR1DTAAR1 | |
| SCHEMBL9945420 | 0.81 | KCNA3 (0.47) | KCNA3PKMHTR1BHTR1DTAAR1 | |
| SCHEMBL29638993 | 0.76 | LTA4H (0.57) | KCNA3PKMLTA4HCHRNB2CHRNB4 | |
| SCHEMBL4142243 | 0.76 | LTA4H (0.57) | KCNA3PKMLTA4HCHRNB2CHRNB4 | |
| SCHEMBL27962 | 0.76 | KCNA3 (0.82) | KCNA3PKMHTR1BHTR1DTAAR1 | |
| SCHEMBL14075083 | 0.75 | KCNA3 (0.58) | KCNA3PKMHTR1BHTR1DTAAR1 | |
| SCHEMBL14667499 | 0.74 | TAAR1 (0.51) | TAAR1ALDH1A1RAB9ADRD2DRD4 | |
| SCHEMBL352124 | 0.74 | KCNA3 (0.56) | KCNA3PKMHTR1BHTR1DTAAR1 | |
| SCHEMBL9944307 | 0.73 | KCNA3 (0.50) | KCNA3HTR1BHTR1DTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772290-B2 | Alpha-arylmethoxyacrylate derivative, preparation method thereof, and pharmaceutical composition containing same | Oscotech Inc. (KR) | 2014-07-08 | — | — | US | disclosed |