SCHEMBL4142243

SCHEMBL4142243

CCC=NOCCOc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.57
PLA2G2A P14555 1/20 0.49
PPARA Q07869 1/20 0.46
KCNA3 P22001 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
PKM P14618 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29638993 1.00 LTA4H (0.57) LTA4HPLA2G2APPARAKCNA3HRH3
SCHEMBL9945420 0.94 KCNA3 (0.47) LTA4HKCNA3PKMCHRNB2CHRNB4
SCHEMBL9945604 0.85 KCNA3 (0.50) LTA4HKCNA3HRH3CHRNB2CHRNB4
SCHEMBL8671305 0.77 LTA4H (0.75) LTA4HPLA2G2APPARAKCNA3HRH3
SCHEMBL15865982 0.76 KCNA3 (0.50) LTA4HKCNA3PKMCHRNB2CHRNB4
SCHEMBL10793769 0.76 MAPT (0.40)
SCHEMBL10791275 0.76 ACACB (0.34)
SCHEMBL4134492 0.75 LTA4H (0.40) LTA4HPPARA
SCHEMBL13545912 0.74 LTA4H (1.00) LTA4HPLA2G2APPARAKCNA3HRH3
SCHEMBL27845338 0.74 LTA4H (0.84) LTA4HPLA2G2APPARAKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300293-A Mixture of antigrowth agent and dextrin SUMITOMO CHEMICAL CO., LTD. (JP) 1994-04-05 US claimed
US-8263099-B2 Insect growth regulating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-11 US disclosed
US-20090246239-A1 INSECT GROWTH REGULATING COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
US-20090081307-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2009-03-26 US disclosed
US-20090062350-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2009-03-05 US disclosed
US-20090060966-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2009-03-05 US disclosed
US-20050202057-A1 Insect growth regulating composition SUMITOMO CHEMICAL COMPANY, LIMITED 2005-09-15 US disclosed
US-5116826-A SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed