Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889374 | 0.79 | GRIA1 (0.43) | NOTUMGRIA1 | |
| SCHEMBL19105578 | 0.71 | OPRM1 (0.40) | — | |
| SCHEMBL12205781 | 0.69 | GRIA1 (0.36) | GRIA1 | |
| SCHEMBL24927470 | 0.69 | ELANE (0.36) | NOTUMCASR | |
| SCHEMBL2609420 | 0.68 | CASR (0.48) | CASR | |
| SCHEMBL23368132 | 0.68 | ELOVL1 (0.39) | CASRGRIA1 | |
| SCHEMBL18782798 | 0.67 | GRIA1 (0.39) | CASRGRIA1 | |
| SCHEMBL23176116 | 0.67 | CASR (0.40) | NOTUMCASR | |
| SCHEMBL15980624 | 0.67 | NOTUM (0.44) | NOTUMCASR | |
| SCHEMBL15980636 | 0.67 | GRIA1 (0.51) | GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140193363-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140193363-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | NOTUM 1717/4885CASR 4817/4885GRIA1 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.