Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869775 | 1.00 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL1987507 | 1.00 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL1985449 | 0.80 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL1992104 | 0.77 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL15869705 | 0.77 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL15869747 | 0.77 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL1986397 | 0.77 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL1986086 | 0.76 | CYP1A2 (0.30) | — | |
| SCHEMBL1988370 | 0.73 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL1986973 | 0.73 | CHRNA7 (0.45) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778959-B2 | AZA-bridged ring-fused indoles and indolines | ABBVIE INC. (US) | 2014-07-15 | — | — | US | claimed |
| US-8778959-B2 | AZA-bridged ring-fused indoles and indolines | ABBVIE INC. (US) | 2014-07-15 | — | — | US | disclosed |