SCHEMBL15869780

SCHEMBL15869780

O=C(Cc1cccc(Cl)c1)c1ccc(C(=O)Cc2cccc(Cl)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.65
MAPT P10636 1/20 0.65
PIK3CA P42336 1/20 0.61
CTBP2 P56545 1/20 0.57
HTR3E A5X5Y0 1/20 0.55
HTR3B O95264 1/20 0.55
HTR3A P46098 1/20 0.55
HTR3D Q70Z44 1/20 0.55
HTR3C Q8WXA8 1/20 0.55
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
RXRG P48443 1/20 0.51
HDAC1 Q13547 3/20 0.50
MEN1 O00255 2/20 0.50
ALDH1A1 P00352 2/20 0.50
KMT2A Q03164 2/20 0.50
EPHX2 P34913 1/20 0.50
MAOA P21397 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9991701 0.96 L3MBTL1 (0.71) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL1515772 0.93 MAPT (0.66) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL30511469 0.93 MAPT (0.66) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL8956360 0.92 GRIN2B (0.56) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL27476708 0.88 PIK3CA (0.54) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL9315539 0.87 MAPT (0.52) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL15191689 0.85 PIK3CA (0.51) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL15968691 0.84 PIK3CA (0.50) L3MBTL1MAPTPIK3CACTBP2HTR3E
SCHEMBL11172110 0.82 CTBP2 (0.62) PIK3CACTBP2HTR3EHTR3BHTR3A
SCHEMBL31405561 0.81 ERCC5 (0.56) L3MBTL1MAPTPIK3CACTBP2HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9102694-B1 Method for bottom-up graphene sheet preparation and bandgap engineering HRL LABORATORIES, LLC (US) 2015-08-11 US claimed
US-9102694-B1 Method for bottom-up graphene sheet preparation and bandgap engineering HRL LABORATORIES, LLC (US) 2015-08-11 US disclosed
US-9012917-B1 Method for bottom-up graphene sheet preparation and bandgap engineering HRL LABORATORIES, LLC (US) 2015-04-21 US disclosed
US-8779177-B1 Method for bottom-up graphene sheet preparation and bandgap engineering HRL LABORATORIES, LLC (US) 2014-07-15 US disclosed