Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869780 | 0.88 | L3MBTL1 (0.65) | PIK3CAL3MBTL1MAPTCTBP2HTR3E | |
| SCHEMBL30511469 | 0.85 | MAPT (0.66) | PIK3CAL3MBTL1MAPTCTBP2HTR3E | |
| SCHEMBL9991701 | 0.85 | L3MBTL1 (0.71) | PIK3CAL3MBTL1MAPTCTBP2HTR3E | |
| SCHEMBL1515772 | 0.85 | MAPT (0.66) | PIK3CAL3MBTL1MAPTCTBP2HTR3E | |
| SCHEMBL8956360 | 0.81 | GRIN2B (0.56) | PIK3CAL3MBTL1MAPTCTBP2HTR3E | |
| SCHEMBL27494960 | 0.81 | EGFR (0.43) | L3MBTL1MAPTNPC1RAB9AMAOB | |
| SCHEMBL27557474 | 0.81 | SLC1A1 (0.43) | L3MBTL1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL3248951 | 0.79 | MAPT (0.61) | L3MBTL1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL3037831 | 0.79 | S1PR5 (0.53) | PIK3CAL3MBTL1MAPTMEN1ALDH1A1 | |
| SCHEMBL9315539 | 0.77 | MAPT (0.52) | PIK3CAL3MBTL1MAPTCTBP2HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1616432-A | Compound,its use and pharmaceutical compositions comprising same | ELAN PHARM INC (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1171878-C | Compounds, their use and pharmaceutical compositions containing them | ������˹ҩƷ��˾ | 2004-10-20 | — | — | CN | disclosed |
| CN-1242007-A | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds | ELAND PHARMACEUTICAL CORP (US) | 2000-01-19 | — | — | CN | disclosed |