Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 4/20 | 0.34 |
| ▸ | GLP1R | P43220 | 8/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805702 | 0.94 | FURIN (0.32) | FAPGLP1ROPRK1NPY1RNPY4R | |
| SCHEMBL21297142 | 0.93 | FAP (0.35) | FAPHRH1NPY1RNPY4RSIRT2 | |
| SCHEMBL25787322 | 0.93 | FAP (0.35) | FAPHRH1NPY1RNPY4RSIRT2 | |
| SCHEMBL21297140 | 0.93 | FAP (0.35) | FAPHRH1NPY1RNPY4RSIRT2 | |
| SCHEMBL21297079 | 0.93 | FAP (0.35) | FAPHRH1NPY1RNPY4RSIRT2 | |
| SCHEMBL19776684 | 0.93 | GLP1R (0.40) | FAPGLP1RNPY1RFURIN | |
| SCHEMBL22841031 | 0.93 | GLP1R (0.33) | FAPGLP1RHRH1NPY1RNPY4R | |
| SCHEMBL17841870 | 0.93 | GLP1R (0.40) | FAPGLP1RNPY1RFURIN | |
| SCHEMBL22115954 | 0.93 | GLP1R (0.40) | FAPGLP1RNPY1RFURIN | |
| SCHEMBL20263703 | 0.93 | GLP1R (0.40) | FAPGLP1RNPY1RFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089614-B2 | Hydrophilic self-immolative linkers and conjugates thereof | BIOALLIANCE C.V. (NL) | 2015-07-28 | — | — | US | disclosed |
| US-20140193437-A1 | HYDROPHILIC SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF | BIOALLIANCE C.V. (NL) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140193437-A1 | HYDROPHILIC SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF | CD44, ABCG2, MCL1 | FAP 2301/4885GLP1R 583/4885OPRK1 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.