SCHEMBL25787322

SCHEMBL25787322

CNC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 5/20 0.35
▸ MGLL Q99685 1/20 0.34
▸ FURIN P09958 8/20 0.34
▸ SIRT2 Q8IXJ6 1/20 0.34
▸ C3AR1 Q16581 1/20 0.33
▸ HRH1 P35367 2/20 0.33
▸ NPY1R P25929 1/20 0.31
▸ NPY2R P49146 1/20 0.31
▸ NPY4R P50391 1/20 0.31
▸ NPY5R Q15761 1/20 0.31
▸ PRSS1 P07477 1/20 0.31
▸ RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21297140 1.00 FAP (0.35) FAPMGLLFURINSIRT2C3AR1
SCHEMBL21297079 1.00 FAP (0.35) FAPMGLLFURINSIRT2C3AR1
SCHEMBL21297142 1.00 FAP (0.35) FAPMGLLFURINSIRT2C3AR1
SCHEMBL15870228 0.93 FAP (0.34) FAPFURINSIRT2HRH1NPY1R
SCHEMBL31294572 0.93 MGLL (0.36) FAPMGLLFURINC3AR1HRH1
SCHEMBL30781655 0.93 MGLL (0.36) FAPMGLLFURINC3AR1HRH1
SCHEMBL31045369 0.93 MGLL (0.36) FAPMGLLFURINC3AR1HRH1
SCHEMBL30781641 0.93 MGLL (0.36) FAPMGLLFURINC3AR1HRH1
SCHEMBL16870158 0.92 C3AR1 (0.41) FAPMGLLFURINC3AR1
SCHEMBL22133461 0.92 FURIN (0.34) FAPMGLLFURINC3AR1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 FAP 363/4885MGLL 1851/4885FURIN 220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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