Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223510 | 0.77 | NOTUM (0.76) | NPY5RNOTUM | |
| SCHEMBL13209368 | 0.76 | NOTUM (0.54) | NPY5RNOTUMP2RY1 | |
| SCHEMBL13824485 | 0.75 | NOTUM (0.49) | NPY5RNOTUMP2RY1 | |
| SCHEMBL2801717 | 0.75 | HDAC1 (0.65) | NPY5R | |
| SCHEMBL13209390 | 0.73 | P2RY1 (0.55) | NPY5RNOTUMP2RY1 | |
| SCHEMBL13209389 | 0.73 | HDAC1 (0.47) | NPY5RNOTUMP2RY1 | |
| SCHEMBL2354258 | 0.72 | AKT1 (0.43) | NPY5RNOTUM | |
| SCHEMBL13209391 | 0.71 | HDAC1 (0.48) | NOTUMP2RY1 | |
| SCHEMBL30232632 | 0.70 | NOTUM (0.61) | NPY5RNOTUM | |
| SCHEMBL12049087 | 0.70 | HDAC1 (0.59) | P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092531-A1 | Novel Spiropiperidine Compounds | ELI LILLY AND COMPANY (US) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092531-A1 | Novel Spiropiperidine Compounds | REN, SLC5A1, SLC5A2 | NPY5R 524/4885NOTUM 3026/4885P2RY1 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.