Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.36 |
| ▸ | CDK2 | P24941 | 6/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882521 | 0.78 | CSF1R (0.41) | CSF1RKDM4EMAPTMAPK1MEN1 | |
| SCHEMBL15864774 | 0.77 | FYN (0.42) | CSF1RCCNA2CDK2CDK5DYRK1A | |
| SCHEMBL1558215 | 0.77 | CSF1R (0.41) | CSF1RKDM4EMAPTMAPK1MEN1 | |
| SCHEMBL14780159 | 0.76 | CSF1R (0.32) | CSF1RKDM4EMAPTMAPK1MEN1 | |
| SCHEMBL14853695 | 0.73 | FPR2 (0.43) | CSF1RKDM4EMAPTMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL16145403 | 0.72 | FPR2 (0.42) | CSF1RKDM4EMAPTMAPK1MEN1 | |
| SCHEMBL15797990 | 0.72 | CCNC (0.55) | CSF1RKMT2ACCNT1CDK9 | |
| SCHEMBL15797988 | 0.72 | CCNC (0.55) | CSF1RKMT2ACCNT1CDK9 | |
| SCHEMBL15870503 | 0.71 | TRPV3 (0.47) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL15870516 | 0.70 | TRPV3 (0.48) | TRPV3CDK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014106606-A1 | NOVE PHENYL/PYRIDINE SERIES SUBSTITUED BY HYDROXYETHYLAMINO FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2014-07-10 | — | — | WO | disclosed |