Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.71 |
| ▸ | CNR1 | P21554 | 2/20 | 0.64 |
| ▸ | CNR2 | P34972 | 2/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729936 | 1.00 | HLCS (0.71) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL13045403 | 1.00 | HLCS (0.71) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL7376597 | 1.00 | HLCS (0.71) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL12320610 | 1.00 | HLCS (0.71) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL22493325 | 1.00 | HLCS (0.71) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL8240579 | 0.99 | TDP1 (0.72) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL17704089 | 0.99 | TDP1 (0.72) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL6941477 | 0.99 | TDP1 (0.72) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL18513310 | 0.96 | TDP1 (0.66) | HLCSTDP1CNR1CNR2F2 | |
| SCHEMBL17881931 | 0.96 | TDP1 (0.71) | HLCSTDP1CNR1CNR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140193831-A1 | SEED TRAIT PREDICTION BY ACTIVITY-BASED PROTEIN PROFILING | GAUTIER SEMENCES (FR) | 2014-07-10 | — | — | US | disclosed |