Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569602 | 0.86 | TDP1 (0.59) | TDP1LMNAALDH1A1TP53POLB | |
| SCHEMBL8853249 | 0.78 | TDP1 (0.62) | TDP1LMNAALDH1A1TP53POLB | |
| SCHEMBL12327084 | 0.78 | TDP1 (0.50) | TDP1LMNAALDH1A1TP53POLB | |
| SCHEMBL11453340 | 0.77 | TNF (0.53) | TDP1LMNAALDH1A1POLBMAPK1 | |
| SCHEMBL9076943 | 0.76 | TDP1 (0.56) | TDP1LMNAALDH1A1TP53POLB | |
| SCHEMBL30423475 | 0.75 | TDP1 (0.54) | TDP1LMNAASAH1ALDH1A1POLB | |
| SCHEMBL29257418 | 0.75 | TDP1 (0.54) | TDP1LMNAASAH1ALDH1A1POLB | |
| SCHEMBL8732975 | 0.74 | TDP1 (0.61) | TDP1LMNAALDH1A1TP53POLB | |
| SCHEMBL1757227 | 0.74 | TDP1 (0.53) | TDP1LMNAALDH1A1POLBHTT | |
| SCHEMBL15870698 | 0.74 | KMT2A (0.52) | ALDH1A1POLBHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096519-B2 | Process for the synthesis of ketones from internal alkenes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140194604-A1 | PROCESS FOR THE SYNTHESIS OF KETONES FROM INTERNAL ALKENES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194604-A1 | PROCESS FOR THE SYNTHESIS OF KETONES FROM INTERNAL ALKENES | FASN, NOTUM, DGAT2 | TDP1 3875/4885LMNA 3348/4885ASAH1 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.