SCHEMBL8853249

SCHEMBL8853249

CC(CC(=O)O)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.62
LMNA P02545 1/20 0.56
TNF P01375 1/20 0.55
ALDH1A1 P00352 5/20 0.53
POLB P06746 3/20 0.53
TP53 P04637 2/20 0.53
KDM4E B2RXH2 1/20 0.53
GLA P06280 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
NFKB1 P19838 1/20 0.53
APEX1 P27695 1/20 0.53
MAPK1 P28482 1/20 0.53
HSD17B10 Q99714 1/20 0.53
GAA P10253 1/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
PDE4A P27815 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28569602 0.87 TDP1 (0.59) TDP1LMNATNFALDH1A1POLB
SCHEMBL9076943 0.84 TDP1 (0.56) TDP1LMNATNFALDH1A1POLB
SCHEMBL7215852 0.83 TDP1 (0.55) TDP1LMNATNFALDH1A1POLB
SCHEMBL21149874 0.83 LMNA (0.53) TDP1LMNATNFALDH1A1POLB
SCHEMBL21685881 0.83 POLB (0.67) TDP1LMNATNFALDH1A1POLB
SCHEMBL21149873 0.83 LMNA (0.53) TDP1LMNATNFALDH1A1POLB
SCHEMBL30371843 0.83 LMNA (0.53) TDP1LMNATNFALDH1A1POLB
SCHEMBL12942067 0.81 ALDH1A1 (0.56) TDP1LMNATNFALDH1A1POLB
SCHEMBL1757227 0.81 TDP1 (0.53) TDP1LMNATNFALDH1A1POLB
SCHEMBL28908606 0.81 TNF (0.60) TDP1LMNATNFALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4360665-A 4\"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor ELI LILLY AND COMPANY (US) 1982-11-23 US claimed
US-20250059184-A1 IMIDAZOPYRIDINE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2025-02-20 US disclosed
WO-2023114844-A1 IMIDAZOPYRIDINE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. (US) 2023-06-22 WO disclosed
US-5688434-A BLEACHING TEXTILES BY APPLYING BLEACHING AGENT AUSIMONT S.P.A. (IT) 1997-11-18 US disclosed
US-5575947-A BLEACH AUSIMONT S.R.L. (IT) 1996-11-19 US disclosed
EP-0325288-B1 IMIDO-AROMATIC PERCARBOXYLIC ACIDS AUSIMONT S.p.A. (IT) 1993-09-01 EP disclosed
EP-0325289-B1 BLEACHING AGENTS COMPRISING IMIDO-AROMATIC PERCARBOXYLIC ACIDS AUSIMONT S.p.A. (IT) 1993-09-01 EP disclosed
EP-0325289-A1 Bleaching agents comprising imido-aromatic percarboxylic acids AUSIMONT S.p.A. (IT) 1989-07-26 EP disclosed
EP-0325288-A1 Imido-aromatic percarboxylic acids AUSIMONT S.p.A. (IT) 1989-07-26 EP disclosed
US-4360665-A 4\"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor ELI LILLY AND COMPANY (US) 1982-11-23 US disclosed
US-4012413-A 1-(2-AMINOALKYL)-6-PHENYL-TRIAZOLO-BENZODIAZEPINE COMPOUNDS USED AS TRANQUILIZERS AND ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059184-A1 IMIDAZOPYRIDINE PSYCHOPLASTOGENS AND USES THEREOF GRIN2A, GAP43, GRIN2C TDP1 436/4885LMNA 3785/4885TNF 4449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.