Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19185131 | 0.83 | NPC1 (0.41) | MGLL | |
| SCHEMBL15490605 | 0.79 | FAAH (0.36) | FAAHMGLLAKR1C3ABL1SRC | |
| SCHEMBL17507092 | 0.78 | ALDH1A1 (0.46) | AKR1C3 | |
| SCHEMBL15883177 | 0.77 | FAAH (0.34) | FAAHMGLLABL1SRC | |
| SCHEMBL5441070 | 0.76 | MEN1 (0.36) | FAAHMGLLAKR1C3ABL1SRC | |
| SCHEMBL5447292 | 0.74 | MEN1 (0.38) | FAAHMGLLABL1 | |
| SCHEMBL15488349 | 0.72 | FAAH (0.31) | FAAHMGLLAKR1C3 | |
| SCHEMBL1919863 | 0.72 | AKR1C3 (0.44) | AKR1C3ABL1 | |
| SCHEMBL15492619 | 0.69 | — | — | |
| SCHEMBL15875300 | 0.68 | FAAH (0.47) | FAAHMGLLAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718779-B2 | Intermediate and polymorphs of 1-(4-methoxypheny1)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | MSN LABORATORIES LIMITED (IN) | 2017-08-01 | — | — | US | claimed |
| US-20150353541-A1 | Novel intermediate and polymorphs of 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | THIRUMALAI RAJAN SRINIVASAN (US) | 2015-12-10 | — | — | US | claimed |
| WO-2015177801-A1 | NOVEL PROCESS FOR THE PREPARATION OF A LACTAM-CONTAINING COMPOUND | SYMED LABS LIMITED (IN) | 2015-11-26 | — | — | WO | claimed |
| WO-2014108919-A2 | NOVEL INTERMEDIATE AND POLYMORPHS OF 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-c] PYRIDINE-3-CARBOXAMIDE AND PROCESS THEREOF | MSN LABORATORIES LIMITED (IN) | 2014-07-17 | — | — | WO | claimed |
| US-20180087079-A1 | METHODS OF USING CELL-CYCLE INHIBITORS TO MODULATE ONE OR MORE PROPERTIES OF A CELL CULTURE | AMGEN INC. (US) | 2018-03-29 | — | — | US | disclosed |
| US-9718779-B2 | Intermediate and polymorphs of 1-(4-methoxypheny1)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | MSN LABORATORIES LIMITED (IN) | 2017-08-01 | — | — | US | disclosed |
| US-9718779-B2 | Intermediate and polymorphs of 1-(4-methoxypheny1)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | MSN LABORATORIES LIMITED (IN) | 2017-08-01 | — | — | US | disclosed |
| US-9718779-B2 | Intermediate and polymorphs of 1-(4-methoxypheny1)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | MSN LABORATORIES LIMITED (IN) | 2017-08-01 | — | — | US | disclosed |
| US-20150353542-A1 | METHODS OF USING CELL-CYCLE INHIBITORS TO MODULATE ONE OR MORE PROPERTIES OF A CELL CULTURE | AMGEN INC. (US) | 2015-12-10 | — | — | US | disclosed |
| US-20150353541-A1 | Novel intermediate and polymorphs of 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | THIRUMALAI RAJAN SRINIVASAN (US) | 2015-12-10 | — | — | US | disclosed |
| US-20150353541-A1 | Novel intermediate and polymorphs of 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | THIRUMALAI RAJAN SRINIVASAN (US) | 2015-12-10 | — | — | US | disclosed |
| US-20150353541-A1 | Novel intermediate and polymorphs of 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | THIRUMALAI RAJAN SRINIVASAN (US) | 2015-12-10 | — | — | US | disclosed |
| WO-2015177801-A1 | NOVEL PROCESS FOR THE PREPARATION OF A LACTAM-CONTAINING COMPOUND | SYMED LABS LIMITED (IN) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015177801-A1 | NOVEL PROCESS FOR THE PREPARATION OF A LACTAM-CONTAINING COMPOUND | SYMED LABS LIMITED (IN) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015177801-A1 | NOVEL PROCESS FOR THE PREPARATION OF A LACTAM-CONTAINING COMPOUND | SYMED LABS LIMITED (IN) | 2015-11-26 | — | — | WO | disclosed |
| WO-2014108919-A2 | NOVEL INTERMEDIATE AND POLYMORPHS OF 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-c] PYRIDINE-3-CARBOXAMIDE AND PROCESS THEREOF | MSN LABORATORIES LIMITED (IN) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014108919-A2 | NOVEL INTERMEDIATE AND POLYMORPHS OF 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-c] PYRIDINE-3-CARBOXAMIDE AND PROCESS THEREOF | MSN LABORATORIES LIMITED (IN) | 2014-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353541-A1 | Novel intermediate and polymorphs of 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra hydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and process thereof | CYP3A4, CYP4B1, CYP1A1 | FAAH 4157/4885MGLL 4869/4885AKR1C3 842/4885 |
| US-20180087079-A1 | METHODS OF USING CELL-CYCLE INHIBITORS TO MODULATE ONE OR MORE PROPERTIES OF A CELL CULTURE | CDKN1A, CDC25C, CDC25B | FAAH 3349/4885MGLL 4097/4885AKR1C3 4075/4885 |
| US-20150353542-A1 | METHODS OF USING CELL-CYCLE INHIBITORS TO MODULATE ONE OR MORE PROPERTIES OF A CELL CULTURE | CDKN1A, CDC25C, CDC25B | FAAH 3349/4885MGLL 4097/4885AKR1C3 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.