Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874771 | 0.83 | MEN1 (0.37) | L3MBTL1ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL15874896 | 0.83 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL15875499 | 0.76 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL25170022 | 0.70 | FFAR1 (0.50) | L3MBTL1ALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL15883224 | 0.69 | MEN1 (0.38) | L3MBTL1ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL25173221 | 0.68 | FFAR1 (0.48) | L3MBTL1ALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL3874916 | 0.68 | FFAR1 (0.45) | L3MBTL1ALDH1A1MAPK1TSHR | |
| SCHEMBL25170005 | 0.68 | FFAR1 (0.56) | L3MBTL1ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL25172823 | 0.67 | HCAR2 (0.48) | L3MBTL1ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL3498873 | 0.67 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1MAPK1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943494-A1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | Eli Lilly and Company (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014110000-A1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 2014-07-17 | — | — | WO | disclosed |