Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120570 | 0.75 | CYP1A2 (0.47) | SMN1; SMN2KDM4E | |
| SCHEMBL11328828 | 0.74 | MCL1 (0.48) | MCL1SMN1; SMN2PRNPRXFP1KDM4E | |
| SCHEMBL14246796 | 0.74 | MCL1 (0.48) | MCL1SMN1; SMN2PRNPRXFP1KDM4E | |
| SCHEMBL7970697 | 0.74 | MCL1 (0.58) | MCL1SMN1; SMN2PRNPRXFP1KDM4E | |
| SCHEMBL584871 | 0.74 | RXFP1 (0.71) | MCL1PRNPRXFP1KDM4EKMT2A | |
| SCHEMBL29939764 | 0.74 | RXFP1 (0.71) | MCL1PRNPRXFP1KDM4EKMT2A | |
| SCHEMBL11730019 | 0.72 | RXFP1 (0.47) | MCL1SMN1; SMN2PRNPRXFP1KDM4E | |
| SCHEMBL5852644 | 0.71 | ALDH1A1 (0.65) | SMN1; SMN2KMT2ARECQLHPGD | |
| SCHEMBL29448323 | 0.69 | PRNP (0.53) | MCL1PRNPRXFP1KDM4EKMT2A | |
| SCHEMBL1398747 | 0.69 | PRNP (0.53) | MCL1PRNPRXFP1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107325002-B | Method for synthesizing aryl halide by taking aryl carboxylic acid as raw material | 南昌大学 | 2020-03-27 | — | — | CN | disclosed |
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |