Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25238621 | 0.83 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL25317043 | 0.74 | SLC6A3 (0.55) | SLC6A3SLC6A4SLC6A2ALDH1A1CYP1A2 | |
| SCHEMBL13982727 | 0.74 | MAPT (0.60) | SLC6A3SLC6A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL21200837 | 0.74 | SLC6A4 (0.95) | SLC6A3SLC6A4SLC6A2ALDH1A1KMT2A | |
| SCHEMBL29867630 | 0.74 | SLC6A4 (0.95) | SLC6A3SLC6A4SLC6A2ALDH1A1KMT2A | |
| SCHEMBL2107714 | 0.73 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6999838 | 0.73 | SLC6A3 (0.85) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5651714 | 0.71 | ALDH1A1 (0.57) | ALDH1A1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL17612857 | 0.71 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2ALDH1A1KDM4E | |
| SCHEMBL25237787 | 0.71 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |