Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666971 | 0.83 | ALDH1A1 (0.50) | TDP1GSTP1ALDH1A1MEN1KMT2A | |
| SCHEMBL30239985 | 0.82 | GSTP1 (0.53) | TDP1GSTP1PTGESALDH1A1MEN1 | |
| SCHEMBL28988353 | 0.82 | GSTP1 (0.53) | TDP1GSTP1PTGESALDH1A1MEN1 | |
| SCHEMBL14979389 | 0.82 | ALDH1A1 (0.61) | TDP1CYP1A2GSTP1ALDH1A1MEN1 | |
| SCHEMBL3514226 | 0.82 | ALDH1A1 (0.61) | TDP1ATMPTGESALDH1A1MEN1 | |
| SCHEMBL15876274 | 0.82 | TSHR (0.50) | TDP1CYP1A2CYP2A6GSTP1ALDH1A1 | |
| SCHEMBL13828623 | 0.82 | CYP2A6 (0.47) | TDP1CYP2A6GSTP1PTGESALDH1A1 | |
| SCHEMBL30397482 | 0.80 | TDP1 (0.58) | TDP1ATMPTGESALDH1A1MEN1 | |
| SCHEMBL2501029 | 0.80 | TDP1 (0.58) | TDP1ATMPTGESALDH1A1MEN1 | |
| SCHEMBL13828956 | 0.79 | GSTP1 (0.44) | TDP1CYP2A6GSTP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094165-A | Method for preparing biaryl compound by Suzuki coupling reaction | 浙江省化工研究院有限公司 | 2020-12-18 | — | — | CN | disclosed |
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |