Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.41 |
| ▸ | EIF4E | P06730 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501029 | 1.00 | TDP1 (0.58) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL2497892 | 0.87 | TDP1 (0.53) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL2500091 | 0.85 | ALDH1A1 (0.55) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL18302787 | 0.81 | TDP1 (0.55) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL1559947 | 0.81 | ALDH1A1 (0.59) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL11619067 | 0.81 | TDP1 (0.55) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL29962750 | 0.81 | ALDH1A1 (0.59) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29962919 | 0.81 | TDP1 (0.50) | TDP1ATMALDH1A1VCAM1EIF4E | |
| SCHEMBL2499499 | 0.81 | TDP1 (0.50) | TDP1ATMALDH1A1VCAM1EIF4E | |
| SCHEMBL28107557 | 0.80 | TDP1 (0.53) | TDP1ATMALDH1A1HIF1AHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253646-A | Synthesis method and application of 2-nitro-1, 1' -biphenyl compound | 湖南海利化工股份有限公司 | 2023-06-13 | — | — | CN | disclosed |