Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.62 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | ALAD | P13716 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15877409 | 0.87 | DAO (0.74) | DAOACMSDMAPTNPSR1ALAD | |
| SCHEMBL4398550 | 0.77 | DAO (1.00) | DAOMAPTNPSR1ALADPOLB | |
| SCHEMBL2843937 | 0.76 | AGXT (0.59) | ACMSDPTPN5BCL2AOC3IDH1 | |
| SCHEMBL1761887 | 0.75 | ALAD (0.59) | DAOALADMEN1POLBRAB9A | |
| SCHEMBL505511 | 0.75 | ALAD (0.70) | DAOALADMEN1POLBRAB9A | |
| SCHEMBL23189011 | 0.74 | MAPT (0.79) | DAOMAPTNPSR1MEN1POLB | |
| SCHEMBL30760383 | 0.74 | DAO (0.56) | DAOMAPTNPSR1MEN1POLB | |
| SCHEMBL20344489 | 0.74 | DAO (0.56) | DAOMAPTNPSR1MEN1POLB | |
| SCHEMBL31498881 | 0.74 | CALM1 (0.60) | ACMSDPTPN5AOC3IDH1 | |
| SCHEMBL9625135 | 0.74 | CALM1 (0.60) | ACMSDPTPN5AOC3IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729455-A1 | BIARYL DERIVATIVES AS NACHR MODULATORS | Lupin Limited (IN) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013005153-A1 | BIARYL DERIVATIVES AS NACHR MODULATORS | LUPIN LIMITED (IN) | 2013-01-10 | — | — | WO | disclosed |