Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411424 | 0.76 | GRM2 (0.36) | GRM2KCNMA1KDM4ELMNASLC9A1 | |
| SCHEMBL5183293 | 0.72 | KCNMA1 (0.59) | GRM2KCNMA1LMNAP2RX7 | |
| SCHEMBL10825780 | 0.66 | GRM2 (0.46) | GRM2KDM4ELMNAP2RX7 | |
| SCHEMBL22326123 | 0.65 | SMN1; SMN2 (0.40) | GRM2KCNMA1 | |
| SCHEMBL9777378 | 0.64 | KCNMA1 (0.49) | GRM2KCNMA1 | |
| SCHEMBL14288448 | 0.64 | HTR2A (0.51) | KDM4ELMNA | |
| SCHEMBL8617659 | 0.62 | TSHR (0.47) | CNR2 | |
| SCHEMBL31329335 | 0.62 | ESR2 (0.41) | CNR2P2RX7 | |
| SCHEMBL15873889 | 0.62 | ESR1 (0.36) | CNR2 | |
| SCHEMBL8938827 | 0.61 | NR1I2 (0.43) | GRM2KDM4ELMNADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2765145-B1 | SILYLATED POLYBUTADIENE | NIPPON SODA CO (JP) | 2022-03-02 | — | — | EP | disclosed |
| US-9828448-B2 | Silylated polybutadiene | NIPPON SODA CO., LTD. (JP) | 2017-11-28 | — | — | US | disclosed |
| EP-2765145-A1 | SILYLATED POLYBUTADIENE | Nippon Soda Co., Ltd. (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-20140206789-A1 | SILYLATED POLYBUTADIENE | NIPPON SODA CO., LTD. (JP) | 2014-07-24 | — | — | US | disclosed |