Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628796 | 0.80 | KCNMA1 (0.58) | KCNMA1GRM2ALDH1A1TSHRKCNN4 | |
| SCHEMBL10825780 | 0.77 | GRM2 (0.46) | GRM2ALDH1A1NT5ERORCKMT2A | |
| SCHEMBL80393 | 0.75 | KCNMA1 (1.00) | KCNMA1ALDH1A1TSHRGAAKMT2A | |
| SCHEMBL5411424 | 0.73 | GRM2 (0.36) | KCNMA1GRM2NOTUMKMT2ALMNA | |
| SCHEMBL9777378 | 0.73 | KCNMA1 (0.49) | KCNMA1GRM2ALDH1A1TSHRKCNN4 | |
| SCHEMBL15879441 | 0.72 | GRM2 (0.36) | KCNMA1GRM2LMNAP2RX7 | |
| SCHEMBL8764298 | 0.72 | KCNMA1 (0.51) | KCNMA1ALDH1A1KCNN4GAAGFER | |
| SCHEMBL8938828 | 0.71 | KCNMA1 (0.47) | KCNMA1KCNN4KMT2ALMNA | |
| SCHEMBL22326123 | 0.71 | SMN1; SMN2 (0.40) | KCNMA1GRM2ALDH1A1NT5E | |
| SCHEMBL6064913 | 0.71 | KCNMA1 (0.67) | KCNMA1GAAKMT2AMGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570983-B1 | Material composites made of a moulded part made of transparent or translucent, dyeable plastic thermoplastic moulding compositions | EMS CHEMIE AG (CH) | 2007-10-17 | — | — | EP | disclosed |
| EP-1570983-A1 | Material composites made of a moulded part made of transparent or translucent, dyeable plastic thermoplastic moulding compositions | EMS-Chemie AG (CH) | 2005-09-07 | — | — | EP | disclosed |