SCHEMBL1587973

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5721928	0.88	HPGD (0.81)	HPGDL3MBTL1ALDH1A1MAPTHRH3
	SCHEMBL1587143	0.86	HPGD (0.58)	HPGDL3MBTL1ALDH1A1MAPTHRH3
	SCHEMBL276922	0.82	HTT (0.69)	HPGDL3MBTL1ALDH1A1MAPTHTT
	SCHEMBL2638071	0.81	HPGD (0.86)	HPGDL3MBTL1ALDH1A1MAPTHRH3
	SCHEMBL4111861	0.80	HPGD (0.77)	HPGDL3MBTL1ALDH1A1MAPTHRH3
	SCHEMBL5721752	0.79	HPGD (0.61)	HPGDL3MBTL1ALDH1A1MAPTHRH3
	SCHEMBL1588349	0.79	HPGD (0.76)	HPGDL3MBTL1ALDH1A1MAPTHRH3
	SCHEMBL1587810	0.78	HRH3 (0.59)	HPGDL3MBTL1ALDH1A1MAPTHRH3
	SCHEMBL277558	0.77	MEN1 (0.64)	HPGDL3MBTL1ALDH1A1KDM4EPOLB
	SCHEMBL280182	0.77	ALDH1A1 (0.44)	HPGDL3MBTL1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.