SCHEMBL276922

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL277005	0.84	HTT (0.50)	HTTKMT2ALMNAMAPK1ALDH1A1
	SCHEMBL12313815	0.82	HTT (0.66)	HTTSMN1; SMN2CYP2D6HPGDKMT2A
	SCHEMBL276182	0.82	HTT (0.66)	HTTSMN1; SMN2CYP2D6HPGDKMT2A
	SCHEMBL279600	0.82	HTT (0.69)	HTTSMN1; SMN2CYP2D6HPGDKMT2A
	SCHEMBL277360	0.82	KMT2A (0.69)	HTTSMN1; SMN2CYP2D6KMT2ALMNA
	SCHEMBL1587973	0.82	HPGD (0.76)	HTTSMN1; SMN2HPGDKMT2AALDH1A1
	SCHEMBL14395480	0.81	HTT (0.68)	HTTSMN1; SMN2CYP2D6HPGDKMT2A
	SCHEMBL12265883	0.78	HTT (0.64)	HTTSMN1; SMN2CYP2D6HPGDKMT2A
	SCHEMBL277558	0.77	MEN1 (0.64)	HPGDKMT2ALMNAALDH1A1KDM4E
	SCHEMBL276955	0.76	ALDH1A1 (0.58)	CYP2D6KMT2ALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.